Peyronie’s Disease

What is Peyronie’s Disease?

 

Peyronie’s Disease occurs when scar tissue develops in the penis, causing curvature that makes sex difficult or uncomfortable. It is non-cancerous, but has close association with erectile dysfunction. Peyronie’s Disease is often treated with collagenase clostridium histolyticum (Xiaflex) but more severe cases may require surgery.

 
 
An illustration of a penis that is curved 60 degrees.

What are the symptoms of Peyronie’s Disease?

  • A curved erection with or without pain

    • If you develop a curve in your erection that you didn't notice before, it may be a sign that you could have Peyronie's disease. Some men report they feel pain in their erection as the curve develops for the first 12 to 18 months.

  • A Peyronie’s Plaque

    • This is a bump of scar tissue under the skin of the penis. It's most commonly found on the top side of the penis. Some men can feel it, while others don't notice it.

  • Bothered by your erection

    • Many men with Peyronie's disease report being bothered by the way their curved erection looks and the challenges it presents to their ability to engage in sexual activity.

An illustrated cross-section of a penis with Peyronie's Plaque.

What is Peyronie’s Plaque?

This isn't the kind of plaque that can develop in your arteries. If you feel around the inner part of the bend in your penis you may be able to feel this bump of scar tissue.

If the plaque forms on the top of the penis, it will make the erect penis curve up. If the plaque forms on one side of the penis, the erect penis will curve to that side.

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How common is Peyronie’s Disease?

1 in 10 men may have Peyronie's disease in the US.*

It's more common as men age, especially between the ages of 40 and 70.

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How do I know it’s Peyronie’s Disease?

Many men mistake Peyronie’s Disease for Erectile Dysfunction or cancer. A urologist will typically determine if you have Peyronie’s Disease based on your medical history and a physical examination.

 

Treatments for Peyronie’s Disease

XIAFLEX® (collagenase clostridium histolyticum)

XIAFLEX® is the only nonsurgical treatment option for appropriate adult men with Peyronie's disease approved by the Food and Drug Administration (FDA).

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Surgery

Surgical correction may be your best option if you have a complex curvature or associated erectile dysfunction. Surgical options include plaque excision with grafting, penile plication, or placement of a penile prosthesis. Dr. Pan will guide you through the various treatment options and help you select the optimal approach.

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